Latin American Crosstalk in Biophysics and Physiology. SBF.uy-SAB


November 26-29, 
2015, Salto, Uruguay

Important information regarding the poster presentation:
Posters numbered from 1 to 34, 35 to 65 and 66 to 100 should be appended on November 26, 27 and 28, respectively.
You can check the book abstract clicking here.

Find information and some pictures at facebook page of SBF.uy https://www.facebook.com/SBF.uy/.



SESSIONS:
  • Structure-function of Macromolecules. Chairs: A. Buschiazzo (UY) & A. Vila (ARG)
    • Intrinsic Disorder and Functional Promiscuity in Golgi Reassembly and Stacking Proteins, by Antonio Costa-Filho (Brazil)
    • Role of the metal binding loops in cofactor assembly and electronic structure of a copper site in cytochrome oxidases, by Alejandro Vila (Argentina)
    • Molecular basis of hydroperoxide specificity in peroxiredoxins: studies in AhpE from Mycobacterium tuberculosis, by Ari Zeida (Argentina)
    • Non covalent coupling of proteins to a oligomeric scaffold through high affinity heterodimeric modules, by Particio Craig (Argentina)
  • Structure & Dynamics of Lipid Membranes. Chairs: S. Sanchez (CH) & G. Fidelio (ARG)
    • How defects on lipid membranes can be investigated from Small Angle X-Ray Scattering (SAXS) data, by Rosangela Itri (Brazil)
    • Coupling of surface pressure and osmotic stress: a new model for lipid monolayers/bilayers based on thermodynamic of irreversible processes, by Anibal Disalvo (Argentina)
    • Membrane heterogeneity using laurdan and fluorescence microscopy methods, by Susana Sanchez (Chile)
    • Activity of secreted phospholipases A2 in organized lipid interfaces, bu Gerardo Fidelio (Argentina)
  • Biological Fluorescence and Microscopy. Chairs: D. Jameson (USA) & A. Denicola (UY)
    • Applications of Phasors in Biological Fluorescence, by David Jameson (USA)
    • In vivo physical characterization of lamellar bodies in A549 lung cells using LAURDAN fluorescence, by Leonel Malacrida (Uruguay)
    • Modulation of protein conformation and aggregation of a β-barrel protein family, by Carla Angelani (Argentina)
  • Cellular Biophysics and Physiology. Chairs: P. Schwarzbaum (ARG) & J. Hernandez (UY)
    • Intact Heart Loose Patch Photolysis Reveals Ionic Current Kinetics During Ventricular Action Potentials, by Ariel Escobar (USA)
    • P2X purinergic receptors, the fast sensor of ATP, by Luciano Moffatt (Argentina)
    • Dynamic regulation of cell volume and extracellular ATP of human erythrocytes, by Pablo Schwarzbaum (Argentina)
    • Theoretical approaches to study diffusion in cellular media, by Julio Hernández (Uruguay) 
  • Biotechnology. Chairs: A. Chabalgoity (UY)  & S. Alonso (ARG)
    • Engineering Proteins with Light, by Steffen Petersen (Denmark)
    • Nanotoxicology: Applications on zebra fish model, by Jimena Prieto (Argentina)
    • Protein based nanoparticles by radiation-induced crosslinking, Mariano Grasselli (Argentina)
    • Molecular and cellular bases of new immunotherapies for respiratory infections, by Alejandro Chabalgoity (Uruguay)
  • MembraneTransporters and Channels. Chairs: D. Peluffo (UY) & R. Gonzalez-Lebrero (ARG)
    • PIP aquaporins heterotetramerization, by Karina Alleva (Argentina)
    • Motifs in the permeation pathways of connexin channels that mediate calcium sensing and gating, by Jorge Contreras (USA)
    • Enzymatic requirements for non-canonical downhill proton transport by Na/K pumps, by Pablo Artigas (USA)
    • Two new ion transport mechanisms and their crosstalk : a new hypothesis for the senescence of human erythrocyte, by Jesús Romero (Venezuela)
  • Signalling in Excitable Cells. Chairs: E. Rios (USA) & A. Escobar (USA)
    • Functional modes of the voltage sensor of excitation-contraction coupling in mammalian skeletal muscle, by Gustavo Brum (Uruguay)
    • Dual role of Calcium-Calmodulin dependent Kinase II signaling in cardiac ischemia and reperfusion, by Carlos Valverde (Argentina)
    • Voltage dependent Ca transients in the sarcoplasmic reticulum of frog skeletal muscle, by Gonzalo Pizarro (Uruguay)
    • A possible crosstalk of Ca2+ signals between hair cell synapses during the development of the mammalian inner ear, by Juan Gutman (Argentina)
  • Biomechanics and Complex Systems. Chairs: L. Acerenza (UY) & C. Biancardi (IT)
    • Axolotl spinal cord regeneration triggered by cell proliferation: a quantitative biology approach, by Osvaldo Chara (Germany)
    • 19th century British jumpers reinvented halteres and extended Olympians' range by ante litteram rocket propulsion, by Alberto Minetti (Italy)
    • Racehorses and greyhounds, two models for investigating the biomechanics of transverse and rotary gallop, by Carlos Biancardi (Uruguay)
    • Systems biology approaches for predicting the behavior of complex systems, by Luis Acerenza (Uruguay)
  • Computational Biophysics. Chairs: L. Coitiño (UY) & D. Estrin (ARG)
    • Pore formation and lipid rearrangements during the translocation of CPP-decorated nanoparticles across membranes, by Mario del Pópolo (Argentina)
    • Direct Simulation of Electrophysiology Experiments in Connexin Hemichannels, by Sergio Pantano (Uruguay)
    • Development and use of efficient hybrid QM/MM simulation schemes, by Mariano González-Lebrero (Argentina)
    • Modeling the catalytic cycle of the atypical 2-Cys PRDX5: roles of active-site residues and folding, by Stephanie Portillo (Uruguay)  
  • Young Investigators. Chairs: L. Gonzalez-Flecha (ARG) & M. Machado (UY)
    • Muscle coordination in explosive movements: a potential alternative method for study through electromyography, by Germán Pequera (Uruguay)
    • Microtubule Buckling Dynamics in Living Cells, by Carla Pallaveccini (Argentina)
    • Probing solvent accessible surface area in proteins: an NMR approach, by José María Delfíno (Argentina)
  • L. Bagatolli and R. Grigera books presentations. Chair: E. Mizraji (UY)
    • Vida ¿una cuestión de grasas? Una perspectiva desde la Biofísica de Membranas, Ed Yachay (Ecuador), by Luis Bagatolli (Denmark)
    • Temas de Biofisicoquímica, Ed UBA, by Raúl Grigera (Argentina)


PLENARY LECTURES:
  • MANUEL PRIETO (Centro de Química-Física Molecular, Instituto Superior Técnico, Lisboa, Portugal) 

Research Topics: Application of spectroscopic techniques (UV-Vis absorption, steady-state and time-resolved fluorescence, fluorescence anisotropy, dynamic and static light scattering) to the study of supramolecular aggregates and structural problems (e.g., localization and dynamics), compounds of biological relevance in interaction with membrane model systems.



Talk Title: Amyloid-like fibers and the role of lipids: Structure and dynamics from advanced FRET methodologies and microscopy.




  • THOMAS HEIMBURG (Membrane Biophysics Group, Niels Bohr Institute - University of Copenhagen, Denmark) 

Research Topics: Experimental and theoretical physics of synthetic and biological membranes. Physics of membrane fluctuations, the action potential, anesthesia and lipid membrane channels. Neurosciences.




Talk Title: The physics of nerves.





  • LUIS BAGATOLLI (MEMPHYS Center for Biomembrane Physics, Departament of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark)

Research Topics: My current research interests are related to physicochemical (biophysical) aspects of biological systems, particularly the effect of non-equilibrium conditions, crowding and spatial confinement in membranous systems and cells. I am also interested in the development and applications of biphotonic-related techniques to biological systems (fluorescence spectroscopy, imaging techniques based in multiphoton excitation microscopy).




Talk Title: Tight coupling of metabolic oscillations and intracellular water dynamics in Saccharomyces cerevisiae.




  • JUAN CARMELO GÓMEZ-FERNÁNDEZ (Grupo de Biomembranas, Universidad de Murcia, Murcia, España)


Research Topics:
My current research interests are related to the intereaction with lipids of PKCs isoenzymes and also to molecular interactions in membranes.





Talk Title: Membrane Lipid Activation of Protein Kinases C.




  • FELIX GOÑI (Unidad de Biofísica, CSIC-Universidad del País Vasco/EHU, España)

Research Topics:
Membrane Biophysics, sphingolipids and sphingomyelinases, surfactants, membrane fusion, structure-function relationships in membrane proteins, membrane proteomics, lipid-protein interactions.



Talk Title: Novel 1-deoxy-(dihydro)ceramides occurring in mammalian cells.





  • CECILIA BOUZAT (Instituto de Investigaciones Biológicas de Bahía Blanca, Argentina)

Research Topics: 
Mechanisms and the structural basis of Cys-loop receptor-mediated synaptic transmission, understanding the causes of abnormal function of these receptors, and deciphering the molecular action of drugs affecting neuronal communication.



Talk Title: Exploring Activation and Modulation of Cys-loop Receptors as Drug Targets.



  • EDUARDO MIZRAJI (Sección Biofísica, Unidad de Biología Celular, Facultad de Ciencias, Universidad de la República, Uruguay)

Research Topics:
The theory of neural networks and information processing in biological systems. Development of an algebraic formalism for logical operators inspired by matrix representations of distributed memories. Relationships between connectivity and stability in complex systems.



Talk Title: Spatial and temporal neural computations driven by words.


  • RAFAEL RADI (Departamento de Bioquímica, Centro de Investigaciones Biomedicas (CEINBIO), Facultad de Medicina, Universidad de la República, Uruguay)

Research Topics: The production, chemical biology, cell signaling actions and pathological effects of oxidants and free radicals. Biochemical mechanisms of the pathogenic actions of nitric oxide through its interaction with superoxide radicals and the formation of peroxynitrite. Relevance to disease processes including atherogenesis, hypertension, neurodegeneration and inflammation.


Talk Title: Peroxynitrite, a stealthy biological oxidant.


Program:





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Leonel Malacrida,
18 nov 2015, 16:27